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Filtered Search Results
Medchemexpress LLC Mal-VC-PAB-DM1 | 1464051-44-2 | MFCD10039825 | 99.4% | 1248.81 g/mol | C61H82ClN9O17 | 5 MG
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Mal-VC-PAB-DM1 is a drug-linker conjugate used in the construction of antibody-drug conjugates (ADCs). It links the cytotoxic payload DM1 to a cleavable valine-citrulline-p-aminobenzyl (vc-pab) linker to enable targeted delivery of the payload in ADC research. The compound is supplied as a high-purity material and is soluble in DMSO for research applications.
- Drug-linker conjugate for ADC research
- Contains DM1 microtubule-disrupting payload
- Cleavable valine-citrulline-p-aminobenzyl (vc-pab) linker
- High purity (99.4%)
- Molecular weight 1248.81 g/mol
- Soluble in DMSO
- CAS number 1464051-44-2
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Medchemexpress LLC Zanubrutinib | 1691249-45-2 | MFCD31567461 | 471.55 | C27H29N5O3 | 25 MG
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Zanubrutinib is a selective, irreversible small-molecule inhibitor of Bruton tyrosine kinase (BTK) used in research to study BTK signaling and pharmacology. The compound shows high biochemical potency and is supplied as a solid reagent suitable for analytical, biochemical, and cellular studies. This catalog item is provided for research use only.
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Medchemexpress LLC 1,4-dimethoxybenzene-d10 | 74079-00-8 | 98.0% | 148.23 g/mol | C8D10O2 | 25 MG
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1,4-Dimethoxybenzene-d10 is the deuterium-labeled form of 1,4-dimethoxybenzene used as an analytical standard and tracer in research. It is employed as an internal standard for NMR, GC-MS, and LC-MS applications, and in metabolic and aromatic profiling studies. The compound has formula C8D10O2 and high isotopic enrichment (about 98 atom % D).
- Deuterium-labeled internal standard for NMR, GC-MS, and LC-MS
- High isotopic enrichment for reliable quantitation
- Suitable tracer for metabolic and aromatic profiling studies
- Stable solid form for convenient storage and handling
- Compatible with common analytical solvents and methods
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Medchemexpress LLC Rg-12525 | 120128-20-3 | 98.3% | 423.47 g/mol | C25H21N5O2 | 50 MG
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RG-12525 (NID 525) is a small-molecule research compound that antagonizes peptidoleukotriene receptors (LTC4, LTD4, LTE4), exhibits PPAR-γ agonist activity, and inhibits cytochrome P450 enzymes. It is provided in high-purity solid form and as a DMSO solution for biochemical and pharmacological research, supporting both in vitro and in vivo investigations.
- Potent leukotriene receptor antagonist with low-nanomolar activity.
- Shows PPAR-γ agonist activity (≈60 nM).
- Inhibits CYP3A4 (Ki ≈0.5 μM), useful for metabolism studies.
- Available as solid and DMSO solution for flexible dosing.
- High purity suitable for biochemical and pharmacological assays.
- Applicable to in vitro and in vivo pharmacology research.
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Medchemexpress LLC HY-101253 5mg Medchemexpress, AM-92016 (hydrochloride) CAS:133229-11-5 Purity:>98%
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Medchemexpress, HY-101253 5mg AM-92016 (hydrochloride) CAS:133229-11-5 AM-92016 hydrochloride is a specific blocker of rectifier potassium current ( IK ). AM-92016 hydrochloride delays rectifier potassium channel (IK), repolarizes the membrane thereby restricting the duration of the nerve impulse thereby restricting the duration of the nerve impulse [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-117113 5mg Medchemexpress, JI051 CAS:2234281-75-3 Purity:>98%
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Medchemexpress, HY-117113 5mg JI051 CAS:2234281-75-3 JI051 is a stabilizer for the Hes1-PHB2 interaction, interacts with a cancer-associated protein chaperone prohibitin 2 ( PHB2 ), induces cell-cycle arrest by inhibiting the Notch downstream effector gene Hes1. Anti-cancer activity [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Epertinib hydrochloride | 2071195-74-7 | 98.2% | 596.48 g/mol | C30H28Cl2FN5O3 | 25 MG
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Epertinib hydrochloride is a research-grade, orally active, reversible tyrosine kinase inhibitor selective for EGFR, HER2, and HER4. Supplied as a solid hydrochloride salt, it is intended for in vitro and preclinical research and should be handled according to its safety data sheet.
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Medchemexpress LLC HY-109096 10mg Medchemexpress, Nidufexor CAS:1773489-72-7 Purity:>98%
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Medchemexpress, HY-109096 10mg Nidufexor CAS:1773489-72-7 Nidufexor is a farnesoid X receptor (FXR) agonist. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-N0693 10mg Medchemexpress, Schisandrin A CAS:61281-38-7 Purity:>98%
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Medchemexpress, HY-N0693 10mg Schisandrin A CAS:61281-38-7 Schisandrin A inhibits CYP3A activity with an IC 50 of 6.60 μM and K i of 5.83 μM, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Matrix Scientific BIS(PENTAFLUOROPHENYL)CARBO-5G
Bis(pentafluorophenyl)carbonate, 97%; 5g,C13F10O3, MFCD00368353, mw 394.13, [59483-84-0]
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eMolecules 770-35-4 | 1-Phenoxy-2-propanol, tech. | Oakwood Chemical | MFCD00016861 | 152.193 | C9H12O2 | 85.000 | CC(O)COc1ccccc1 | 25g | 537708078
1-Phenoxy-2-propanol, tech. | Oakwood Chemical | 770-35-4 | MFCD00016861 | 152.193 | C9H12O2 | 85.000 | CC(O)COc1ccccc1 | 25g | 537708078
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Apexbio Technology LLC PND-1186 10MM IN 1ML DMSO
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PND-1186 10MM IN 1ML DMSO APEXBIO TECHNOLOGIES
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![eMolecules 76824-16-3 | 3-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]propanamide | Toronto Research Chemicals | MFCD27966021 | 259.350 | C8H13N5OS2 | 95.000 | NC(=O)CCSCc1csc(N=C(N)N)n1 | 100mg | 483378710](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502177356.JPG-250.jpg)
eMolecules 76824-16-3 | 3-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]propanamide | Toronto Research Chemicals | MFCD27966021 | 259.350 | C8H13N5OS2 | 95.000 | NC(=O)CCSCc1csc(N=C(N)N)n1 | 100mg | 483378710
3-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]propanamide | Toronto Research Chemicals | 76824-16-3 | MFCD27966021 | 259.350 | C8H13N5OS2 | 95.000 | NC(=O)CCSCc1csc(N=C(N)N)n1 | 100mg | 483378710
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Medchemexpress LLC HY-12420 5mg Medchemexpress, JNJ-47117096 hydrochloride CAS:1610536-69-0 Purity:>98%
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Medchemexpress, HY-12420 5mg JNJ-47117096 hydrochloride CAS:1610536-69-0 JNJ-47117096 hydrochloride is potent and selective MELK inhibitor, with an IC50 of 23 nM, also effectively inhibits Flt3, with an IC50 of 18 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC KRAS inhibitor-9 | 300809-71-6 | 99.9% | 292.81 | 100 MG
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KRAS inhibitor-9 is a potent inhibitor of KRAS (Kd=92 μM) that blocks the formation of GTP-KRAS and downstream activation of KRAS signaling pathways. It binds to KRAS G12D, KRAS G12C, and KRAS Q61H proteins with moderate binding affinities. This product is intended for research use only.
- Causes G2/M cell cycle arrest and induces apoptosis in non-small cell lung cancer (NSCLC) cells
- Selectively inhibits the proliferation of NSCLC cells with KRAS mutation but does not affect normal lung cells
- Inhibits the activation of the KRAS downstream signaling pathway
- Blocks GTP-KRAS formation
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